Immunity to smallpox and vaccinia: the future of smallpox vaccines
نویسندگان
چکیده
منابع مشابه
Developing new smallpox vaccines.
New stockpiles of smallpox vaccine are required as a contingency for protecting civilian and military personnel against deliberate dissemination of smallpox virus by terrorists or unfriendly governments. The smallpox vaccine in the current stockpile consists of a live animal poxvirus (Vaccinia virus [VACV]) that was grown on the skin of calves. Because of potential issues with controlling this ...
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One of the infectious diseases that was widespread in Fars province during the first Pahlavi era (1925-1941) was smallpox. This disease spread in the early days of the Pahlavi dynasty in the cities of Fars province and its epidemic reached its peak in 1318 AD. Important measures were taken to control the disease, including smallpox inoculation. The smallpox inoculators tried to control the dise...
متن کاملFrom Jenner to modern smallpox vaccines.
Edward Jenner, born in 1749, grew up in Berkeley, Gloucestershire, and pursued his interest in medicine in London where he became a student and lifelong close friend of John Hunter the anatomist and surgeon. Jenner returned to Gloucestershire in 1772. At that time, smallpox was an infectious scourge affecting mainly children. Most who reached adulthood had been exposed to the disease with a cas...
متن کاملGeneralized Vaccinia 2 Days after Smallpox Revaccination
To the Editor: Hospital and public health personnel are currently receiving smallpox vaccination in a national effort to increase preparedness for a possible deliberate release of smallpox (1). Generalized vaccinia (GV) is a typically self-limited adverse event following vaccination (incidence 23.4–238.2 cases per million primary vaccinees and 1.2–10.8 cases per million revaccinees) (2,3). We r...
متن کاملHumoral immunity to smallpox vaccines and monkeypox virus challenge: proteomic assessment and clinical correlations.
Despite the eradication of smallpox, orthopoxviruses (OPV) remain public health concerns. Efforts to develop new therapeutics and vaccines for smallpox continue through their evaluation in animal models despite limited understanding of the specific correlates of protective immunity. Recent monkeypox virus challenge studies have established the black-tailed prairie dog (Cynomys ludovicianus) as ...
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ژورنال
عنوان ژورنال: Expert Review of Clinical Immunology
سال: 2006
ISSN: 1744-666X,1744-8409
DOI: 10.1586/1744666x.2.3.325